See whether this information is useful:
http://support.microsoft.com/kb/314060
Hi Ron,
I have a similar problem and this is the advice I have been given.
Hope it helps.
Daibach98
"Ron Sellner" wrote:
> When booting up, BIOS recognized my CD/DVD RW optical drive and I can boot
> from it. Once Windows has control, my optical drive does not appear on either
> Disk Management or Windows Explorer. When I load a disk, it does not
> autoplay. When I try the Run command, the browser does not show my internal
> optical drive as an option.
>
> I have no problems with the external CD/DVD RW drive (USB). I have tried
> substituting several optical drives that work with Vista on my other
> desktops. The problem is only on the desktop that has Ultimate installed. The
> other two have Home Premium Vista, but they were installed from the 32 bit
> Vista DVD. The desktop with the non-recognition problem is running 64 bit
> Vista Ultimate.