Hi Roger,
I tried the F5 key and no response.
DVD and CD windows close when removed and I do believe the function of the
CF card window closed when removed at one time. I don't know when this
problem of not closing after removal started to happen. Maybe a possible
update for Vista x64 could have caused it. I'm lost and have no idea

The
system itself is extremely stable and I really love it, I've checked all
system drivers and device manager, says everything is ok.
I did purchase Adobe Lightroom to process my RAW images and it did install
an auto recognition to see if there is a card in the CF reader, this function
launches Lightroom. Maybe that caused the problem, I have to check that out.