Dr. Strangelove

There are various methods and tools to clean up trash files, temp files,
personal settings, Office temp, restore points, IE temp, etc, etc. And,
there are a multitude of places for the trash to accumulate. However, there
is no one list of what to clean, where to clean, how to clean, and in what
order.

Let's say you have your system tuned and want to do a backup without having
all of the trash, temp, and settings be on the backup. What steps, system
tools (ie Disk Cleanup), and methods do you use?

And, for those of us paranoid about using unknown third party tools, what
manual methods can be used?

Doc