Indeed I have found a solution that was posted on another forum.
Go to:
GameCopyWorld - Iron Man - NoCD No-CD No-DVD Trainers & Game Fixes[MULTI3]%20No-DVD/Fixed%20EXE
There you can download a fix and the unzipping program for it. Once installed, I was able to play the game, so I kept my Iron Man instead of returning it.
The game is ok and the graphics aren't great. But it's a nice, easy game to play when you're not in the mood for heavy games like Rainbow 6 Vegas 2 or Halo, etc.
There's some rumor that they're going to redo this game and port it from the Xbox 360, instead of the PS2 like this game is. But it's just rumor right now.