Calmat
Use CCleaner to remove the junkfiles. Forget about the registry errors. I have them too, fixing them will not improve performance, but fixing them may cause problems. Others may come by and tell you to use Ccleaner to fix the registry errors because it will not do any harm and they may be right, but I counter and say it will not do any good either.
Even after you use ccleaner, you may show junkfiles. Junk depends on the definition used. Worst case scenario, they may take up a little room. You may be able to get rid of a few additional files by using the disc clean up that is part of Vista.
Disk Cleanup

The types of registry problems can vary quite a bit. The most commonly reported are entries that are orphaned, meaning they reference something that doesn't exist on the computer (like remnants of a program that was uninstalled). It's not really a problem leaving them behind. Is it OK to remove them? Probably.

Where I think a lot of these cleaners go wrong is that they get too invasive. They look at entries that aren't referenced by anything and expect it is OK to remove them. However, I've been told by some techies that these cleaners will remove keys that were there by default from Microsoft. Usually removing them isn't a problem, as worthwhile programs will be intelligent enough to check for registry keys it relies upon, creating them if it doesn't find them. But less robust software will be tripped up and either fail or not work quite right, leaving the user quite frustrated.

I concur about registry fixes. I don't do them. I have seen thread after thread of people with registry problems after using these so called registry fixers.

Originally Posted by calmat

thanks for your help

You're welcome, and thanks for the rep!