Vista - Registry cleaners! need advice

I believe that is the Superfetch feature, which is faster than the prefetch in XP. The more you use Vista, the more it learns about what programs you like to use more often and will preload some of the files so that the applications you like the most will load faster when you need them.

glad so many of us are using ccleaner. check out the other tools at Piriform - The best software is free! and they are all free!! Ive been using ccleaner for the past 3+ years +/-. never let me down!

also "sandboxie" is a great little program to avoid adding any rubbish to your reg or pc in general.

64 bit Registry Cleaner - CleanMyPC Registry Cleaner x64 edition
try this , ths works good n has a few utilities.
make sure u uncheck "file-path" reference , the last item of check registry function as u know there r lots of files in vista which exist for softwares u have not yet installed
n dont tell me u cant find a key for this

CCleaner and Tune Up Utilities would always bork up my Cinema4D installation, to the point where I would have to reinstall. I don't like using registry cleaners for that very reason. However, registry defragmenters would be useful.

There were a couple of good registry cleaners like Advanced WindowsCare (the free version of which could be considered adware, but it's not malware) that didn't bork up my XP box, but I'm a little afraid of trying them on Vista because of other posts that indicate that it messes with your Disk Cleanup utility, causing most of your data to be deleted. I'm a very careful computer user after several years of trial and error, and if I'm gonna pay that much for a PC or a laptop, I'm darn sure not going to mess it up in my zeal to keep it clean.