I have used photo editing software on both and have seen no diffrence, that is they both display the same amount of colours at the same resolution. The difference would be in the way a piece of software written for vista would operate. When software for vista is written then you may notice a slight change because of the way vista handles memory and other under the bonnet devices. At the moment I am using paint.net as I refuse to pay alot of money for software when there is good free software available.