I've surfed the net and found many vista users with the same issue, unfortunately no working solutions out there for most of us. I get a message during setup (usually right around MenuVoices.bsa) saying:
C:\Program Files (x86)\Bethesda Softworks\Fallout 3\Data\Fallout - MenuVoices.bsa doesn't match the file in setup's.cab file. The medium from which you are running the setup may be corrupted; contact your software vendor.
I get a catastrophic failure if I click "Retry" and setup closes. Every subsequent file gives the same error message if I click "Ignore" and setup fails. Any ideas????