My mouse curser ran wild, moving and clicking on its own.

It was not the remote Microsoft mouse.

First I ran anti-virus programs, anti-spyware programs and anti-everything
else programs, but the mouse still ran wild.

As a last resort I went to the Microsoft beta Vista online Safety scan
program and let it run. That scan found a number of issues including
registry issues. After a reboot the mouse problem was gone. Sure wish I knew
just what was the cause, but there you have it.