Hello mrmike,
There are a couple of things you can try, but it seems this game does have a few issues.
The first thing is to turn off Indexing, i had problems with a game and turned this off, (3 days without a crash), i don't know why this works, or even if this will work for you, but worth a go.
Try launching the game from the game folder, not the shortcut, in the game folder launch with the game .EXE, not the launcher.
Lastly, if the none of the above work, you could try a No CD patch, that will sometimes do the trick.
I hope one of these will get the game running for you, good luck and post your results.