Well you always have to launch it through applocale, but you can make an applocale shortcut
so you don't ever have to see it.
The shortcut just launches the app automatically/silently through applocale with the setting you selected when creating it.
You'll see this screen after choosing a language. (only if the language you pick is not already your default for nonunicode.)
The shortcut is then placed in:
%userprofile%\AppData\Roaming\Microsoft\Windows\Start Menu\Programs\Microsoft AppLocale
I normally take it and replace what ever shortcut I used to use, with the new one.
And there you go, still launches through applocale
but you never have to actually see it or configure it for that program. The patch
I linked to, only removes
the stupid reminder warning you get when trying to launch applocale or an applocale shortcut. This