It says it is compatible with Vista,
System Requirements
Operating System Compatibility

WINDOWS XP1, WINDOWS VISTA
Processor Speed

INTEL PENTIUM IV, 1.2 GHz
RAM

512 MB minimum
Hard Disk Space

200 megabytes
Language Support

English, French, Italian, German, Spanish, Japanese, Korean, Chinese Traditional, Chinese Simplified, Portuguese, Czech, Turkish, Polish, Russian
1WINDOWS XP SP2 or later is required
EASYSHARE Software Downloads
Oh and it is free to download (always has been). As to how well it works, no idea as I have just been using Vista's own Picture Gallery (or the Windows Live Photo Gallery) with a couple of older (DX6340 and a CX4230) Kodak cameras. Also if you haven't connected the camera to the computer yet, you probably won't need to install drivers (Vista already had drivers for both of mine; x86 on one computer and x64 on the other).