I could find nothing whatsoever about this filename (except this post - LOL). That usually suggests it may be a remnant of some malware that your AV/AM program mostly but didn't fully remove. Let's try the following:
Go to http://technet.microsoft.com/en-us/sysinternals/bb963902.aspx and run Autoruns (which is a much superior product to msconfig and a great thing to have in the toolkit) and click on the Everything Tab. Look for trerkPl.dll and when you find it uncheck the box to stop it from starting at startup. Check the whole list as there may be more than one entry. When done, click OK and reboot. The message should be gone.
If that doesn't work, try a clean boot http://support.microsoft.com/kb/929135. If the problem goes away then it's just a matter of tracking down the culprit causing the problem. Follow the procedures in the article. Once found, delete, remove, deactivate, or uninstall it. Once done be sure to reset Vista back to normal status as explained in the procedures. If the problem occurs in clean mode then just restore the system to normal status and reboot - this solution is not going to work.
File names like this which produce no results are randomly generated names. I will tell you now that the currently circulating malware with randomly generated names in this AppData folder are not the nicest bunch. This needs a good look.
1 x 640Gb (SATA 300)
Western Digital: WDC WD6400AAKS-75A7B0
1 x 1Tb (SATA 600)
Western Digital: Caviar Black, SATA 6GB/S, 64Mb cache, 8ms
Western Digital: WDC WD1002FAEX-00Z3A0 ATA Device
PSU
Stock PSU - 375W
Case
Dell XPS 420
Cooling
Stock Fan
Mouse
Advent Optical ADE-WG01 (colour change light up)
Keyboard
Dell Bluetooth
Internet Speed
120 kb/s
Other Info
ASUS USB 3.0 5Gbps/SATA 6Gbps - PCI-Express Combo Controller Card (U3S6)
Hi Lorien,niemiro, thanks for your reply's and suggestions, you both seemed to indicate that it pointed to an infection, So i ran norton,(i only have norton because it comes free with my comcast internet) Malwarebytes, Spybot, and Superantispyware, I didn't reboot after each one, but one of them did the trick, and got rid of the popup box,I also want to thank you Lorien for suggesting, http://technet.microsoft.com/en-us/sysinternals/bb963902.aspx and as you say a great thing to have in your toolkit, Thanks again and i tipped the scales for you both, Patch41
It was our pleasure. I'm glad we were able to help.
We appreciate the feedback (and the rep) very much. It was nice of you to let us know how it turned out.
Don't forget to close out the thread by clicking the far right triangular icon at the top of your post and typing "solved" in the box and submitting it. The moderators will notice and put a green check next to the thread title. That way others seeking answers by searching the forums will know that this thread contains a solution to the issue identified in the title - and people seeking to help will not waste time checking out this thread since it has been resolved.